{
  "source_commit": "9ee593ef458cd19764467aacf0df0f4a5ed7d02e",
  "period_seconds": 0.9333333333333333,
  "rate_bpm": 64.28571428571428,
  "phase_samples": 8192,
  "asset_sha256": {
    "physiology.json": "0e62fc3974aefad5f4f0722150e3ce2d2836c406bf4f3bd3bf0a92ca8fde6c77",
    "flow-in.bin.gz": "398930e00ca6baf0589deecfa809f2a9d1a0ea795a47e3d90641aae9fd38a95e",
    "flow-out.bin.gz": "096bca62d4ec3609ff4558ebca9cd617c954ede658242fb6e2e12ba8f2298c21",
    "blood-domains.bin.gz": "16595ca2dcb6e7489245b798426b25ca429973dc1cd91dbc7027b1470f23cfb3",
    "flow-vortex.bin.gz": "5cdf291bc7b52f4b9fc4fdc0a623281ef3933f3d418cafcbeb0a001b7db17fad"
  },
  "regions": [
    {
      "name": "LV",
      "edv_ml": 107.34188721211356,
      "esv_ml": 48.10802934632385,
      "ed_phase": 0.0877685546875,
      "es_phase": 0.44140625,
      "volume_excursion_ml": 59.23385786578971,
      "ef_percent": 55.182426361426174,
      "inflow_integral_ml": 72.87694454265161,
      "outflow_integral_ml": 72.87694454265163,
      "peak_inflow_ml_s": 373.93587515459876,
      "peak_outflow_ml_s": 345.26677866535033,
      "peak_outflow_phase": 0.189697265625,
      "peak_inflow_phase": 0.5635986328125,
      "inflow_peaks": [
        {
          "phase": 0.0162353515625,
          "flux_ml_s": 198.45425589178853
        },
        {
          "phase": 0.5635986328125,
          "flux_ml_s": 373.93587515459876
        }
      ],
      "balance_max_error_ml_s": 0.0,
      "outflow_outside_ed_to_es_ml": 13.643074499327216
    },
    {
      "name": "RV",
      "edv_ml": 111.17542135314734,
      "esv_ml": 61.37462551969363,
      "ed_phase": 0.037109375,
      "es_phase": 0.4278564453125,
      "volume_excursion_ml": 49.80079583345371,
      "ef_percent": 44.79478937638752,
      "inflow_integral_ml": 55.432245589534226,
      "outflow_integral_ml": 55.43224558953424,
      "peak_inflow_ml_s": 226.28233708822364,
      "peak_outflow_ml_s": 205.66273147795914,
      "peak_outflow_phase": 0.1510009765625,
      "peak_inflow_phase": 0.57568359375,
      "inflow_peaks": [
        {
          "phase": 0.57568359375,
          "flux_ml_s": 226.28233708822364
        },
        {
          "phase": 0.9569091796875,
          "flux_ml_s": 139.32010624507672
        }
      ],
      "balance_max_error_ml_s": 0.0,
      "outflow_outside_ed_to_es_ml": 5.631445070769613
    },
    {
      "name": "LA",
      "edv_ml": 73.26014339172517,
      "esv_ml": 48.044674076363776,
      "ed_phase": 0.545654296875,
      "es_phase": 0.0531005859375,
      "volume_excursion_ml": 25.21546931536139,
      "ef_percent": 34.41908266618205,
      "inflow_integral_ml": 72.87694454265161,
      "outflow_integral_ml": 72.87694454265161,
      "peak_inflow_ml_s": 362.0854731150225,
      "peak_outflow_ml_s": 373.93587515459876,
      "peak_outflow_phase": 0.5635986328125,
      "peak_inflow_phase": 0.54833984375,
      "inflow_peaks": [
        {
          "phase": 0.04150390625,
          "flux_ml_s": 148.29054996293488
        },
        {
          "phase": 0.181884765625,
          "flux_ml_s": 94.14096195533205
        },
        {
          "phase": 0.54833984375,
          "flux_ml_s": 362.0854731150225
        },
        {
          "phase": 0.77099609375,
          "flux_ml_s": 79.54222987899651
        }
      ],
      "balance_max_error_ml_s": 2.842170943040401e-14,
      "outflow_outside_ed_to_es_ml": 21.730599546246673
    },
    {
      "name": "RA",
      "edv_ml": 83.56737579678588,
      "esv_ml": 45.7503991125418,
      "ed_phase": 0.48193359375,
      "es_phase": 0.0416259765625,
      "volume_excursion_ml": 37.81697668424408,
      "ef_percent": 45.25327775782398,
      "inflow_integral_ml": 55.43224558953423,
      "outflow_integral_ml": 55.432245589534226,
      "peak_inflow_ml_s": 135.0668743044054,
      "peak_outflow_ml_s": 226.28233708822364,
      "peak_outflow_phase": 0.57568359375,
      "peak_inflow_phase": 0.51220703125,
      "inflow_peaks": [
        {
          "phase": 0.14892578125,
          "flux_ml_s": 132.76025718714166
        },
        {
          "phase": 0.3284912109375,
          "flux_ml_s": 104.80859245428343
        },
        {
          "phase": 0.51220703125,
          "flux_ml_s": 135.0668743044054
        },
        {
          "phase": 0.7923583984375,
          "flux_ml_s": 40.2423348536144
        },
        {
          "phase": 0.992431640625,
          "flux_ml_s": 4.082259427850801
        }
      ],
      "balance_max_error_ml_s": 1.4210854715202004e-14,
      "outflow_outside_ed_to_es_ml": 3.176615685645708
    },
    {
      "name": "Ao",
      "edv_ml": 52.182163649187764,
      "esv_ml": 36.92705754854939,
      "ed_phase": 0.529052734375,
      "es_phase": 0.7982177734375,
      "volume_excursion_ml": 15.255106100638372,
      "ef_percent": 29.234330341677627,
      "inflow_integral_ml": 72.87694454265163,
      "outflow_integral_ml": 72.87694454265163,
      "peak_inflow_ml_s": 345.26677866535033,
      "peak_outflow_ml_s": 345.26677866535033,
      "peak_outflow_phase": 0.189697265625,
      "peak_inflow_phase": 0.189697265625,
      "inflow_peaks": [
        {
          "phase": 0.189697265625,
          "flux_ml_s": 345.26677866535033
        },
        {
          "phase": 0.359375,
          "flux_ml_s": 110.72713743129056
        },
        {
          "phase": 0.853271484375,
          "flux_ml_s": 110.13234864584449
        }
      ],
      "balance_max_error_ml_s": 100.85821840426314,
      "outflow_outside_ed_to_es_ml": 69.51425161320239
    },
    {
      "name": "PA",
      "edv_ml": 28.73887134630274,
      "esv_ml": 23.615836826420693,
      "ed_phase": 0.5477294921875,
      "es_phase": 0.9342041015625,
      "volume_excursion_ml": 5.123034519882047,
      "ef_percent": 17.826150714652638,
      "inflow_integral_ml": 55.43224558953424,
      "outflow_integral_ml": 55.43224558953424,
      "peak_inflow_ml_s": 205.66273147795914,
      "peak_outflow_ml_s": 205.66273147795914,
      "peak_outflow_phase": 0.1510009765625,
      "peak_inflow_phase": 0.1510009765625,
      "inflow_peaks": [
        {
          "phase": 0.1510009765625,
          "flux_ml_s": 205.66273147795914
        },
        {
          "phase": 0.8026123046875,
          "flux_ml_s": 72.17243150964438
        }
      ],
      "balance_max_error_ml_s": 25.960891431108575,
      "outflow_outside_ed_to_es_ml": 49.800800518764625
    }
  ],
  "left_right_outflow_difference_ml": 17.44469895311739,
  "left_right_outflow_difference_percent_of_right": 31.470308964735494,
  "doppler_settings": {
    "frequency_mhz": 4.5,
    "prf_khz": 4.0,
    "depth_mm": 150,
    "nyquist_cm_s": 34.22222222222222,
    "depth_prf_limit_khz": 5.133333333333334,
    "maximum_nyquist_at_depth_cm_s": 43.918518518518525,
    "bse_initial_regurgitation_colour_scale_cm_s": [
      50,
      60
    ],
    "comparison_at_3mhz_4khz_cm_s": 51.33333333333333
  },
  "reference_interface_unit_checks": [
    {
      "name": "mitral",
      "upstream_label": 3,
      "downstream_label": 1,
      "shared_staircase_area_cm2": 3.00609375,
      "upstream_limit_flux_per_unit_transfer": 0.03307513987924903,
      "downstream_limit_flux_per_unit_transfer": 0.022518269773572686,
      "note": "Reference grid, no wall motion, unit upstream outlet and downstream inlet; this is a continuity diagnostic, not measured effective valve area."
    },
    {
      "name": "tricuspid",
      "upstream_label": 4,
      "downstream_label": 2,
      "shared_staircase_area_cm2": 6.50375,
      "upstream_limit_flux_per_unit_transfer": 0.014354518871754408,
      "downstream_limit_flux_per_unit_transfer": 0.032828788652084766,
      "note": "Reference grid, no wall motion, unit upstream outlet and downstream inlet; this is a continuity diagnostic, not measured effective valve area."
    },
    {
      "name": "aortic",
      "upstream_label": 1,
      "downstream_label": 5,
      "shared_staircase_area_cm2": 2.8359375,
      "upstream_limit_flux_per_unit_transfer": 0.05659922695206478,
      "downstream_limit_flux_per_unit_transfer": 0.04478272350691259,
      "note": "Reference grid, no wall motion, unit upstream outlet and downstream inlet; this is a continuity diagnostic, not measured effective valve area."
    },
    {
      "name": "pulmonary",
      "upstream_label": 2,
      "downstream_label": 6,
      "shared_staircase_area_cm2": 3.554375,
      "upstream_limit_flux_per_unit_transfer": 0.030355287197977306,
      "downstream_limit_flux_per_unit_transfer": 0.055722893203608695,
      "note": "Reference grid, no wall motion, unit upstream outlet and downstream inlet; this is a continuity diagnostic, not measured effective valve area."
    }
  ],
  "interpretation": [
    "Atria and ventricles balance their fitted volume derivatives algebraically. Aorta and pulmonary artery do not: equal inlet/outlet ignores their fitted volume change.",
    "Negative ventricular volume derivative is routed to outflow even during secondary diastolic volume decreases; no independent valve-state or isovolumic gate exists.",
    "Inlet/outlet fields are built with sources and sinks inside closed chamber domains, not continuity constraints across shared open valve faces.",
    "The interface check diagnoses this construction. Do not call its ratio clinical flow accuracy, or infer true valve area from voxel staircase area.",
    "The current assumed recirculation shape, moving-field transport and reseeded particles do not establish realistic vortex evolution or blood residence time."
  ]
}
